A new jailbreak tweak called SwitchSubstrate is coming soon to Cydia store that will let you disable all Mobile Substrate tweak that you have installed on your iOS device in a single tap without having to dig into SBSettings, which selectively disable certain tweaks and apps.
After installing, SwitchSubstrate icon is added to the Springboard. As soon as you tap for the first time, all custom tweaks will be disabled temporarily, turning your iPhone user interface into stock state. Your iPhone will appear like you haven’t jailbroken it. Clicking the icon second time enables them exactly to the previous state. Watch the video demo of SwitchSubstrate before you decide to get onto your iPhone:
SwitchSubstrate app has not been pushed to Cydia store and once it is available you’ll be able to download the package free of charge.